Paper Info
Title
Patient-specific blood flow simulation to improve intracranial aneurysm diagnosis
Abstract
We present a novel simulation system of blood flow through intracranial aneurysms including the interaction between blood lumen and vessel tissue. It provides the means to estimate rupture risks by calculating the distribution of pressure and shear stresses in the aneurysm, in order to support the planning of clinical interventions. So far, this has only been possible with commercial simulation packages originally targeted at industrial applications, whereas our implementation focuses on the intuitive integration into clinical workflow. Due to the time-critical nature of the application, we exploit most efficient state-of-the-art numerical methods and technologies together with high performance computing infrastructures (Austrian Grid). Our system builds a three-dimensional virtual replica of the patient's cerebrovascular system from X-ray angiography, CT or MR images. The physician can then select a region of interest which is automatically transformed into a tetrahedral mesh. The differential equations for the blood flow and the wall elasticity are discretized via the finite element method (FEM), and the resulting linear equation systems are handled by an algebraic multigrid (AMG) solver. The wall displacement caused by the blood pressure is calculated using an iterative fluid-structure interaction (FSI) algorithm, and the fluid mesh is deformed accordingly. First simulation results on measured patient geometries show good medical relevance for diagnostic decision support.
Year
DOI
Venue
2011
10.1117/12.877983
Proceedings of SPIE
Keywords
DocType
Volume
Intracranial aneurysm,Hemodynamics,Computational fluid dynamics,Finite element method,Fluid-structure interaction
Conference
7964
ISSN
Citations 
PageRank 
0277-786X
0
0.34
References 
Authors
0
2
Name
Order
Citations
PageRank
wolfgang fenz100.68
johannes dirnberger200.68