Name
Title | ||
|---|---|---|
A Wireless Optogenetic Headstage with Multichannel Electrophysiological Recording Capability |
Abstract | ||
|---|---|---|
We present a small and lightweight fully wireless optogenetic headstage capable of optical neural stimulation and electrophysiological recording. The headstage is suitable for conducting experiments with small transgenic rodents, and features two implantable fiber-coupled light-emitting diode (LED) and two electrophysiological recording channels. This system is powered by a small lithium-ion battery and is entirely built using low-cost commercial off-the-shelf components for better flexibility, reduced development time and lower cost. Light stimulation uses customizable stimulation patterns of varying frequency and duty cycle. The optical power that is sourced from the LED is delivered to target light-sensitive neurons using implantable optical fibers, which provide a measured optical power density of 70 mW/mm(2) at the tip. The headstage is using a novel foldable rigid-flex printed circuit board design, which results into a lightweight and compact device. Recording experiments performed in the cerebral cortex of transgenic ChR2 mice under anesthetized conditions show that the proposed headstage can trigger neuronal activity using optical stimulation, while recording microvolt amplitude electrophysiological signals. |
Year | DOI | Venue |
|---|---|---|
2015 | 10.3390/s150922776 | SENSORS |
Keywords | Field | DocType |
neural headstage,optogenetics,neural recording,optical stimulation,wireless sensor,brain-computer interfaces,low-power biotelemetry,electrophysiology | Biomedical engineering,Optical fiber,Optical power,Optogenetics,Duty cycle,Telemetry,Brain–computer interface,Electronic engineering,Engineering,Electrical engineering,Electrophysiology,Microelectrode | Journal |
Volume | Issue | ISSN |
15 | 9.0 | 1424-8220 |
Citations | PageRank | References |
6 | 0.67 | 9 |
Authors | ||
11 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| g gagnonturcotte | 1 | 6 | 0.67 |
| a avakh kisomi | 2 | 6 | 0.67 |
| Reza Ameli | 3 | 15 | 1.88 |
| Camaro, C.-O.Dufresne | 4 | 9 | 1.89 |
| Yoan Lechasseur | 5 | 24 | 3.23 |
| jeanluc neron | 6 | 6 | 0.67 |
| paul bareil | 7 | 6 | 0.67 |
| Paul Fortier | 8 | 101 | 17.51 |
| cyril bories | 9 | 21 | 3.68 |
| Yves De Koninck | 10 | 58 | 8.30 |
| B Gosselin | 11 | 353 | 60.22 |