Paper Info
Title
Synteny Portal: a web-based application portal for synteny block analysis.
Abstract
Recent advances in next-generation sequencing technologies and genome assembly algorithms have enabled the accumulation of a huge volume of genome sequences from various species. This has provided new opportunities for large-scale comparative genomics studies. Identifying and utilizing synteny blocks, which are genomic regions conserved among multiple species, is key to understanding genomic architecture and the evolutionary history of genomes. However, the construction and visualization of such synteny blocks from multiple species are very challenging, especially for biologists with a lack of computational skills. Here, we present Synteny Portal, a versatile web-based application portal for constructing, visualizing and browsing synteny blocks. With Synteny Portal, users can easily (i) construct synteny blocks among multiple species by using prebuilt alignments in the UCSC genome browser database, (ii) visualize and download syntenic relationships as high-quality images, (iii) browse synteny blocks with genetic information and (iv) download the details of synteny blocks to be used as input for downstream synteny-based analyses, all in an intuitive and easy-to-use web-based interface. We believe that Synteny Portal will serve as a highly valuable tool that will enable biologists to easily perform comparative genomics studies by compensating limitations of existing tools. Synteny Portal is freely available at http://bioinfo.konkuk.ac.kr/synteny-portal.
Year
DOI
Venue
2016
10.1093/nar/gkw310
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Synteny,Genome,Biology,Genome browser,Visualization,Comparative genomics,Web application,Genetics,Sequence assembly
Journal
44
Issue
ISSN
Citations 
W1
0305-1048
2
PageRank 
References 
Authors
0.42
17
7
Name
Order
Citations
PageRank
Jongin Lee1124.87
Woonyoung Hong221.10
Minah Cho320.42
Mikang Sim421.44
Daehwan Lee521.44
Youn-Hee Ko6253.44
Jaebum Kim720.42