Title
Computerized detection of masses in digital mammograms: Investigation of feature-analysis techniques
Abstract
Mammographic screening of asymptomatic women has shown effectiveness in the reduction of breast cancer mortality. We are developing a computerized scheme for the detection of mammographic masses as an aid to radiologists in mammographic screening programs. Possible masses on digitized screen/film mammograms are initially identified using a nonlinear bilateral-subtraction technique, which is based on asymmetric density patterns occurring in corresponding portions of right and left mammograms. In this study, we analyze the characteristics of actual masses and nonmass detections to develop feature-analysis techniques with which to reduce the number of non-mass (ie, false-positive) detections. These feature-analysis techniques involve (1) the extraction of various features (such as area, contrast, circularity and border-distance based on the density and geometric information of masses in both processed, and original breast images), and (2) tests of the extracted features to reduce nonmass detections. Cumulative histograms of both actual-mass detections and nonmass detections are used to characterize extracted features and to determine the cutoff values used in the feature tests. The effectiveness of the feature-analysis techniques is evaluated in combination with the computerized detection scheme that uses the nonlinear bilateral-subtraction technique using free-response receiver operating characteristic analysis and 77 patient cases (308 mammograms). Results show that the feature-analysis techniques effectively improve the performance of the computerized detection scheme: about 35% false-positive detections were eliminated without loss in sensitivity when the feature-analysis techniques were used.
Year
DOI
Venue
1994
10.1007/BF03168475
Journal of Digital Imaging
Keywords
Field
DocType
digital mammography, computer-vision, free-response receiver operating characteristic (FROC) analysis, feature analysis, computer-aided diagnosis
Digital mammography,Mammography,Histogram,Computer vision,Computer science,Receiver operating characteristic analysis,Computer-aided diagnosis,Cutoff,Artificial intelligence,Pattern recognition (psychology),Radiographic Image Enhancement
Journal
Volume
Issue
ISSN
7
1
0897-1889
Citations 
PageRank 
References 
8
2.04
0
Authors
5
Name
Order
Citations
PageRank
Fang-Fang Yin1145.24
Maryellen L. Giger239385.89
Kunio Doi382.04
C J Vyborny4438.64
robert a schmidt5258.23