Title
Discovering transnosological molecular basis of human brain diseases using biclustering analysis of integrated gene expression data
Abstract
It has been reported that several brain diseases can be treated as transnosological manner implicating possible common molecular basis under those diseases. However, molecular level commonality among those brain diseases has been largely unexplored. Gene expression analyses of human brain have been used to find genes associated with brain diseases but most of those studies were restricted either to an individual disease or to a couple of diseases. In addition, identifying significant genes in such brain diseases mostly failed when it used typical methods depending on differentially expressed genes.
Year
DOI
Venue
2015
10.1186/1472-6947-15-S1-S7
BMC Med. Inf. & Decision Making
Keywords
Field
DocType
Amyotrophic Lateral Sclerosis, Brain Disease, Unify Medical Language System, Function Enrichment Analysis, GSE28521 Data
Data mining,Disease,Gene,Gene expression,Amyotrophic lateral sclerosis,Human brain,Microarray analysis techniques,Bioinformatics,Biclustering,Health informatics,Medicine
Journal
Volume
Issue
ISSN
15
S-1
1472-6947
Citations 
PageRank 
References 
0
0.34
12
Authors
4
Name
Order
Citations
PageRank
Kihoon Cha141.47
Taeho Hwang2354.12
Kimin Oh361.93
Gwan-Su Yi411110.72