Title
Enhanceosome transcription factors preferentially dimerize with high mobility group proteins.
Abstract
BackgroundThe enhanceosome is an enhancer located upstream of the human interferon β gene, bound by transcription factor (TF) complex of extremely rigid structure. Within these rigid constraints, even a slight change of distances between transcription factor binding sites (TFBS) results in loss of functionality of the enhanceosome. We hypothesized that smaller subunits of the enhanceosome may entail TF complex formation in other regulatory regions.
Year
DOI
Venue
2016
10.1186/s12918-016-0258-3
BMC Systems Biology
Keywords
Field
DocType
Enhanceosome, Transcription factors, Dimerization, High mobility group genes, Enhancers
Interferon,Gene,Biology,DNA binding site,High-mobility group,Cell biology,Enhanceosome,Bioinformatics,Enhancer,Transcription factor,Regulatory sequence
Journal
Volume
Issue
ISSN
10
1
1752-0509
Citations 
PageRank 
References 
0
0.34
4
Authors
4
Name
Order
Citations
PageRank
Aleksander Jankowski1343.47
Paulina Obara200.34
Utsav Mathur300.34
Jerzy Tiuryn41210126.00