Title | ||
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Enhanceosome transcription factors preferentially dimerize with high mobility group proteins. |
Abstract | ||
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BackgroundThe enhanceosome is an enhancer located upstream of the human interferon β gene, bound by transcription factor (TF) complex of extremely rigid structure. Within these rigid constraints, even a slight change of distances between transcription factor binding sites (TFBS) results in loss of functionality of the enhanceosome. We hypothesized that smaller subunits of the enhanceosome may entail TF complex formation in other regulatory regions. |
Year | DOI | Venue |
---|---|---|
2016 | 10.1186/s12918-016-0258-3 | BMC Systems Biology |
Keywords | Field | DocType |
Enhanceosome, Transcription factors, Dimerization, High mobility group genes, Enhancers | Interferon,Gene,Biology,DNA binding site,High-mobility group,Cell biology,Enhanceosome,Bioinformatics,Enhancer,Transcription factor,Regulatory sequence | Journal |
Volume | Issue | ISSN |
10 | 1 | 1752-0509 |
Citations | PageRank | References |
0 | 0.34 | 4 |
Authors | ||
4 |
Name | Order | Citations | PageRank |
---|---|---|---|
Aleksander Jankowski | 1 | 34 | 3.47 |
Paulina Obara | 2 | 0 | 0.34 |
Utsav Mathur | 3 | 0 | 0.34 |
Jerzy Tiuryn | 4 | 1210 | 126.00 |