Title
A Concentration-Controllable Microfluidic Droplet Mixer for Mercury Ion Detection.
Abstract
A microfluidic droplet mixer is developed for rapid detection of Hg(II) ions. Reagent concentration and droplets can be precisely controlled by adjusting the flow rates of different fluid phases. By selecting suitable flow rates of the oil phase, probe phase and sample phase, probe droplets and sample droplets can be matched and merged in pairs and subsequently well-mixed in the poly (dimethylsiloxane) (PDMS) channels. The fluorescence enhancement probe (Rhodamine B mixed with gold nanoparticles) encapsulated in droplets can react with Hg(II) ions. The Hg(II) ion concentration in the sample droplets is adjusted from about 0 to 1000 nM through fluid regulation to simulate possible various contaminative water samples. The intensity of the emission fluorescence is sensitive to Hg(II) ions (increases as the Hg(II) ion concentration increases). Through the analysis of the acquired fluorescence images, the concentration of Hg(II) ions can be precisely detected. With the advantages of less time, cost consumption and easier manipulations, this device would have a great potential in micro-scale sample assays and real-time chemical reaction studies.
Year
DOI
Venue
2015
10.3390/mi6070915
MICROMACHINES
Field
DocType
Volume
Analytical chemistry,Rhodamine B,Colloidal gold,Microfluidics,Fluorescence,Drop (liquid),Materials science,Reagent,Volumetric flow rate,Ion
Journal
6
Issue
Citations 
PageRank 
7
0
0.34
References 
Authors
0
7
Name
Order
Citations
PageRank
Qian-Fang Meng100.34
Lang Rao200.34
Bo Cai3297.09
Su-Jian You400.34
Shi-Shang Guo500.34
Wei Liu6233.19
Xing-Zhong Zhao700.34