Title
Regional quantification of cerebral venous oxygenation from MRI susceptibility during hypercapnia.
Abstract
There is an unmet medical need for noninvasive imaging of regional brain oxygenation to manage stroke, tumor, and neurodegenerative diseases. Oxygenation imaging from magnetic susceptibility in MRI is a promising new technique to measure local venous oxygen extraction fraction (OEF) along the cerebral venous vasculature. However, this approach has not been tested in vivo at different levels of oxygenation. The primary goal of this study was to test whether susceptibility imaging of oxygenation can detect OEF changes induced by hypercapnia, via CO2 inhalation, within selected a priori brain regions.
Year
DOI
Venue
2015
10.1016/j.neuroimage.2014.09.068
NeuroImage
Keywords
Field
DocType
Oxygenation imaging,Oxygen extraction fraction,Hypercapnia,Quantitative susceptibility
Brain mapping,Anesthesia,Cognitive psychology,Hypercapnia,Oxygenation,Cerebral veins,Medicine,Cerebral arteries,Internal medicine,Cardiology,Stroke,Internal Cerebral Vein,Magnetic resonance imaging
Journal
Volume
ISSN
Citations 
104
1053-8119
0
PageRank 
References 
Authors
0.34
10
5
Name
Order
Citations
PageRank
Audrey P Fan100.34
Karleyton C Evans220.71
Jeffrey N Stout320.70
Bruce R Rosen400.34
Elfar Adalsteinsson512916.18