Name
Title | ||
|---|---|---|
Genetically dependent modulation of serotonergic inactivation in the human prefrontal cortex |
Abstract | ||
|---|---|---|
Previous research suggests that genetic variations regulating serotonergic neurotransmission mediate individual differences in the neural network underlying impulsive and aggressive behaviour. Although with conflicting findings, the monoamine oxidase-A (MAOA) and the serotonin transporter (5HTT) gene polymorphisms have been associated with an increased risk to develop impulsive and aggressive behaviour. Double knock-out mice studies have also demonstrated that MAOA and 5HTT genes strongly interact in the metabolic pathway leading to the serotonergic inactivation; however, their potential interactive effect in human brain remains uninvestigated. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1016/j.neuroimage.2007.12.028 | NeuroImage |
Keywords | Field | DocType |
Impulsivity,MAOA,5HTT,Gene polymorphisms,Response inhibition,fMRI | Serotonergic,Developmental psychology,Neuroscience,Monoamine neurotransmitter,Functional magnetic resonance imaging,Prefrontal cortex,Psychology,Brain activity and meditation,Human brain,Serotonin transporter,Anterior cingulate cortex | Journal |
Volume | Issue | ISSN |
40 | 3 | 1053-8119 |
Citations | PageRank | References |
2 | 0.43 | 3 |
Authors | ||
7 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Luca Passamonti | 1 | 43 | 11.28 |
| Antonio Cerasa | 2 | 14 | 2.69 |
| Maria C. Gioia | 3 | 2 | 0.43 |
| Angela Magariello | 4 | 2 | 0.43 |
| Maria Muglia | 5 | 2 | 0.43 |
| Aldo Quattrone | 6 | 12 | 3.83 |
| Francesco Fera | 7 | 2 | 0.77 |