Name
Title | ||
|---|---|---|
Functional re-recruitment of dysfunctional brain areas predicts language recovery in chronic aphasia |
Abstract | ||
|---|---|---|
Functional recovery in response to a brain lesion, such as a stroke, can even occur years after the incident and may be accelerated by effective rehabilitation strategies. In eleven chronic aphasia patients, we administered a short-term intensive language training to improve language functions and to induce cortical reorganization under rigorously controlled conditions. Overt naming performance was assessed during functional magnetic resonance imaging (fMRI) prior to and immediately after the language training. Regions of interest (ROIs) for statistical analyses were constituted by areas with individually determined abnormally high densities of slow wave generators (identified by magnetoencephalography prior to the language intervention) that clustered mainly in left perilesional areas. Three additional individually defined regions served to control for the specificity of the results for the selected respective target region: the homologue area of the individual patient’s lesion, the mirror image of the delta ROI in the right hemisphere and left hemispheric regions that did not produce a significant amount of slow wave activity. |
Year | DOI | Venue |
|---|---|---|
2008 | 10.1016/j.neuroimage.2007.10.008 | NeuroImage |
Field | DocType | Volume |
Rehabilitation,Developmental psychology,Neuroscience,Functional magnetic resonance imaging,Lesion,Dysfunctional family,Psychology,Stroke,Aphasia,Language disorder,Magnetoencephalography | Journal | 39 |
Issue | ISSN | Citations |
4 | 1053-8119 | 8 |
PageRank | References | Authors |
0.96 | 6 | 6 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Marcus Meinzer | 1 | 38 | 5.88 |
| Tobias Flaisch | 2 | 22 | 2.86 |
| Caterina Breitenstein | 3 | 63 | 8.21 |
| Christian Wienbruch | 4 | 19 | 2.72 |
| Thomas Elbert | 5 | 12 | 1.52 |
| Brigitte Rockstroh | 6 | 82 | 10.35 |