Title
Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structures
Abstract
The large amount of imaging data collected in several ongoing multi-center studies requires automated methods to delineate brain structures of interest. We have previously reported on using artificial neural networks (ANN) to define subcortical brain structures. Here we present several automated segmentation methods using multidimensional registration. A direct comparison between template, probability, artificial neural network (ANN) and support vector machine (SVM)-based automated segmentation methods is presented. Three metrics for each segmentation method are reported in the delineation of subcortical and cerebellar brain regions. Results show that the machine learning methods outperform the template and probability-based methods. Utilization of these automated segmentation methods may be as reliable as manual raters and require no rater intervention.
Year
DOI
Venue
2008
10.1016/j.neuroimage.2007.05.063
NeuroImage
Keywords
Field
DocType
Brain segmentation,Registration-based segmentation,Artificial neural networks,Support vector machine,MRI
Brain segmentation,Segmentation,Computer science,Support vector machine,Artificial intelligence,Artificial neural network,Machine learning
Journal
Volume
Issue
ISSN
39
1
1053-8119
Citations 
PageRank 
References 
60
3.20
12
Authors
6
Name
Order
Citations
PageRank
Stephanie Powell1603.20
Vincent Magnotta2603.54
Hans J. Johnson362752.13
Vamsi K. Jammalamadaka4603.20
Ronald Pierson5895.92
Nancy Andreasen612016.35