Name
Abstract | ||
|---|---|---|
Subjective feelings of actual/ideal self-discrepancy vary across individuals and influence one's own affective states. However, the neural correlates of actual/ideal self-discrepancy and their genetic individual differences remain unknown. We investigated neural correlates of actual/ideal self-discrepancy and their associations with the serotonin transporter promoter polymorphism (5-HTTLPR) that moderates human affective states during self-reflection. We scanned short/short and long/long allele carriers of 5-HTTLPR, using functional MRI, during reflection on the distance between actual and ideal self in personality traits. We found that larger actual/ideal self-discrepancy was associated with activations in the ventral/dorsal striatum and dorsal medial and lateral prefrontal cortices. Moreover, these brain activities were stronger in short/short than long/long allele carriers and predicted self-report of life satisfaction in short/short carriers but trait depression in long/long carriers. Our findings revealed neural substrates of actual/ideal self-discrepancy and their associations with affective states that are sensitive to individuals' genetic makeup. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1016/j.neuroimage.2015.08.077 | NeuroImage |
Keywords | Field | DocType |
5-HTTLPR,fMRI,Self-discrepancy,Striatum,Life satisfaction | Life satisfaction,Neural correlates of consciousness,Big Five personality traits,Developmental psychology,Neuroscience,Allele,Trait,Psychology,Serotonin transporter,Affect (psychology),5-HTTLPR | Journal |
Volume | Issue | ISSN |
124 | Pt A | 1053-8119 |
Citations | PageRank | References |
0 | 0.34 | 3 |
Authors | ||
6 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Zhenhao Shi | 1 | 3 | 0.79 |
| Yina Ma | 2 | 13 | 3.20 |
| Bing Wu | 3 | 1 | 1.04 |
| Xinhuai Wu | 4 | 1 | 0.70 |
| Yuanye Wang | 5 | 0 | 0.34 |
| Shihui Han | 6 | 132 | 18.96 |