Title
Parametric imaging and quantitative analysis of the PET amyloid ligand [18F]flutemetamol.
Abstract
•We investigate the application of parametric images methods for [18F]flutemetamol.•We validate kinetics models for [18F]flutemetamol using simulations.•Simulations showed the highest precision and accuracy for SUVR and reference Logan.•Pre-filtered MRTM2 works best for creation of [18F]flutemetamol parametric images.•SUVR images have almost equally high correlation with kinetic modeling as MRTM2.
Year
DOI
Venue
2015
10.1016/j.neuroimage.2015.07.037
NeuroImage
Keywords
Field
DocType
PET,Amyloid imaging,[18F]flutemetamol,Parametric imaging
Standardized uptake value,Nuclear medicine,Voxel,Cognitive psychology,Artificial intelligence,Reference Region,Medicine,Parametric model,Statistical noise,Pattern recognition,Gaussian blur,Parametric statistics,Binding potential
Journal
Volume
ISSN
Citations 
121
1053-8119
1
PageRank 
References 
Authors
0.43
2
5
Name
Order
Citations
PageRank
Kerstin Heurling110.77
C. Buckley286961457.58
Koen Van Laere3437.47
Rik Vandenberghe4315.80
Mark Lubberink5133.78