Title
methylPipe and compEpiTools: a suite of R packages for the integrative analysis of epigenomics data
Abstract
Numerous methods are available to profile several epigenetic marks, providing data with different genome coverage and resolution. Large epigenomic datasets are then generated, and often combined with other high-throughput data, including RNA-seq, ChIP-seq for transcription factors (TFs) binding and DNase-seq experiments. Despite the numerous computational tools covering specific steps in the analysis of large-scale epigenomics data, comprehensive software solutions for their integrative analysis are still missing. Multiple tools must be identified and combined to jointly analyze histone marks, TFs binding and other -omics data together with DNA methylation data, complicating the analysis of these data and their integration with publicly available datasets.
Year
DOI
Venue
2015
10.1186/s12859-015-0742-6
BMC Bioinformatics
Keywords
Field
DocType
Epigenomics, DNA methylation, Histone marks, Integrative biology, High-throughput sequencing
Genome,Biology,Epigenomics,DNA methylation,Software,DNA sequencing,Bioinformatics,Genetics,Histone code,DNA microarray,Epigenetics
Journal
Volume
Issue
ISSN
16
1
1471-2105
Citations 
PageRank 
References 
0
0.34
11
Authors
8