Title
Multiobjective triclustering of time-series transcriptome data reveals key genes of biological processes.
Abstract
Exploratory analysis of multi-dimensional high-throughput datasets, such as microarray gene expression time series, may be instrumental in understanding the genetic programs underlying numerous biological processes. In such datasets, variations in the gene expression profiles are usually observed across replicates and time points. Thus mining the temporal expression patterns in such multi-dimensional datasets may not only provide insights into the key biological processes governing organs to grow and develop but also facilitate the understanding of the underlying complex gene regulatory circuits.
Year
DOI
Venue
2015
10.1186/s12859-015-0635-8
BMC Bioinformatics
Keywords
Field
DocType
Microarray gene expression data, Developmental biology, Tricluster, Multi-objective optimization, Eigen gene, Affirmation score, TRANSFAC
Gene,Biology,Transcriptome,Datasets as Topic,Microarray gene expression,Bioinformatics,Genetics,Gene regulatory network,TRANSFAC,Gene expression profiling,DNA microarray
Journal
Volume
Issue
ISSN
16
1
1471-2105
Citations 
PageRank 
References 
4
0.42
13
Authors
4
Name
Order
Citations
PageRank
Anirban Bhar1121.25
Martin Haubrock243944.78
Anirban Mukhopadhyay371150.07
Edgar Wingender41975322.27