Title
Error correction and statistical analyses for intra-host comparisons of feline immunodeficiency virus diversity from high-throughput sequencing data
Abstract
Infection with feline immunodeficiency virus (FIV) causes an immunosuppressive disease whose consequences are less severe if cats are co-infected with an attenuated FIV strain (PLV). We use virus diversity measurements, which reflect replication ability and the virus response to various conditions, to test whether diversity of virulent FIV in lymphoid tissues is altered in the presence of PLV. Our data consisted of the 3′ half of the FIV genome from three tissues of animals infected with FIV alone, or with FIV and PLV, sequenced by 454 technology.
Year
DOI
Venue
2015
10.1186/s12859-015-0607-z
BMC Bioinformatics
Keywords
Field
DocType
Virus Population Dynamics, Next Generation Sequencing, FIV, Error Correction, Linear Mixed Model, Viral Coinfection
Genome,Virus,CATS,Immunology,Biology,Feline Acquired Immunodeficiency Syndrome,DNA sequencing,Feline immunodeficiency virus,Bioinformatics,Virulence,Virology,DNA microarray
Journal
Volume
Issue
ISSN
16
1
1471-2105
Citations 
PageRank 
References 
0
0.34
10
Authors
6
Name
Order
Citations
PageRank
Yang Liu1182.81
Francesca Chiaromonte253.03
Howard Ross300.34
Raunaq Malhotra453.17
Daniel Elleder500.68
Mary Poss641.79