Title | ||
---|---|---|
Error correction and statistical analyses for intra-host comparisons of feline immunodeficiency virus diversity from high-throughput sequencing data |
Abstract | ||
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Infection with feline immunodeficiency virus (FIV) causes an immunosuppressive disease whose consequences are less severe if cats are co-infected with an attenuated FIV strain (PLV). We use virus diversity measurements, which reflect replication ability and the virus response to various conditions, to test whether diversity of virulent FIV in lymphoid tissues is altered in the presence of PLV. Our data consisted of the 3′ half of the FIV genome from three tissues of animals infected with FIV alone, or with FIV and PLV, sequenced by 454 technology. |
Year | DOI | Venue |
---|---|---|
2015 | 10.1186/s12859-015-0607-z | BMC Bioinformatics |
Keywords | Field | DocType |
Virus Population Dynamics, Next Generation Sequencing, FIV, Error Correction, Linear Mixed Model, Viral Coinfection | Genome,Virus,CATS,Immunology,Biology,Feline Acquired Immunodeficiency Syndrome,DNA sequencing,Feline immunodeficiency virus,Bioinformatics,Virulence,Virology,DNA microarray | Journal |
Volume | Issue | ISSN |
16 | 1 | 1471-2105 |
Citations | PageRank | References |
0 | 0.34 | 10 |
Authors | ||
6 |
Name | Order | Citations | PageRank |
---|---|---|---|
Yang Liu | 1 | 18 | 2.81 |
Francesca Chiaromonte | 2 | 5 | 3.03 |
Howard Ross | 3 | 0 | 0.34 |
Raunaq Malhotra | 4 | 5 | 3.17 |
Daniel Elleder | 5 | 0 | 0.68 |
Mary Poss | 6 | 4 | 1.79 |