Title
Accelerating the Smith-Waterman algorithm with interpair pruning and band optimization for the all-pairs comparison of base sequences
Abstract
The Smith-Waterman algorithm is known to be a more sensitive approach than heuristic algorithms for local sequence alignment algorithms. Despite its sensitivity, a greater time complexity associated with the Smith-Waterman algorithm prevents its application to the all-pairs comparisons of base sequences, which aids in the construction of accurate phylogenetic trees. The aim of this study is to achieve greater acceleration using the Smith-Waterman algorithm (by realizing interpair block pruning and band optimization) compared with that achieved using a previous method that performs intrapair block pruning on graphics processing units (GPUs).
Year
DOI
Venue
2015
10.1186/s12859-015-0744-4
BMC Bioinformatics
Keywords
Field
DocType
Local alignment, Smith-Waterman algorithm, All-pairs comparison, Pruning
Sequence alignment,Graphics,Heuristic,Computer science,Algorithm,Acceleration,Smith–Waterman algorithm,Bioinformatics,Time complexity,Pruning
Journal
Volume
Issue
ISSN
16
1
1471-2105
Citations 
PageRank 
References 
2
0.40
19
Authors
3
Name
Order
Citations
PageRank
Daiki Okada120.40
Fumihiko Ino231738.63
Kenichi Hagihara352856.94