Title
Predicting drug target interactions using meta-path-based semantic network analysis.
Abstract
BackgroundIn the context of drug discovery, drug target interactions (DTIs) can be predicted based on observed topological features of a semantic network across the chemical and biological space. In a semantic network, the types of the nodes and links are different. In order to take into account the heterogeneity of the semantic network, meta-path-based topological patterns were investigated for link prediction.
Year
DOI
Venue
2016
10.1186/s12859-016-1005-x
BMC Bioinformatics
Keywords
Field
DocType
Link prediction,Machine learning,Meta-path topological feature,Random forest,Semantic network analysis
Data mining,Drug discovery,Computer science,Semantic network analysis,Semantic network,Drug target,Artificial intelligence,Bioinformatics,Random forest,Machine learning,Semantic computing
Journal
Volume
Issue
ISSN
17
1
1471-2105
Citations 
PageRank 
References 
13
0.52
19
Authors
6
Name
Order
Citations
PageRank
Gang Fu12079.67
Ying Ding22396144.65
Abhik Seal3382.84
Bin Chen424012.61
Yizhou Sun53446143.93
Evan E Bolton682769.52