Paper Info
Title
Fast Activity Evoked By Intracranial 50 Hz Electrical Stimulation As A Marker Of The Epileptogenic Zone
Abstract
Epilepsy is a disease characterized by aberrant connections between brain areas. The altered activity patterns generated by epileptic networks can be analyzed with intracerebral electrodes during presurgical stereo-electroencephalographic (EEG) monitoring in patients candidate to epilepsy surgery. The responses to high frequency stimulation (HFS) at 50Hz performed for diagnostic purposes during SEEG were analyzed with a new algorithm, to evaluate signal parameters that are masked to visual inspection and to define the boundaries of the epileptogenic network. The analysis was focused on 60-80 Hz activity that represented the largest frequency component evoked by HFS. The distribution of HFS-evoked fast activity across all (up to 162) recording contacts allowed to define different clusters of contacts that retrospectively correlated to the epileptogenic zone identified by the clinicians on the basis of traditional visual analysis. The study demonstrates that computer-assisted analysis of HFS-evoked activities may contribute to the definition of the epileptogenic network on intracranial recordings performed in a pre-surgical setting.
Year
DOI
Venue
2015
10.1142/S0129065715500227
INTERNATIONAL JOURNAL OF NEURAL SYSTEMS
Keywords
Field
DocType
Focal epilepsy, epilepsy surgery, intracerebral recordings, stereo-EEG, high-frequency stimulation
Network on,Neuroscience,Epilepsy surgery,Pattern recognition,Computer science,Epilepsy,Stereoelectroencephalography,Artificial intelligence,Electroencephalography,Stimulation
Journal
Volume
Issue
ISSN
25
5
0129-0657
Citations 
PageRank 
References 
2
0.40
2
Authors
7
Name
Order
Citations
PageRank
Elisa Bellistri131.12
Ivana Sartori2121.03
Veronica Pelliccia321.41
Stefano Francione4181.54
Francesco Cardinale5608.65
Marco de Curtis661.44
Vadym Gnatkovsky740.77