Title
An autonomous in vivo dual selection protocol for boolean genetic circuits.
Abstract
Success in synthetic biology depends on the efficient construction of robust genetic circuitry. However, even the direct engineering of the simplest genetic elements (switches, logic gates) is a challenge and involves intense lab work. As the complexity of biological circuits grows, it becomes more complicated and less fruitful to rely on the rational design paradigm, because it demands many time-...
Year
DOI
Venue
2015
10.1162/ARTL_a_00160
Artificial Life
Keywords
Field
DocType
Directed evolution,dual selection,Boolean genetic circuits,toxin-antitoxin systems,conjugation,individual-based models (IBM),bacterial simulator
Logic gate,Boolean circuit,Computer science,Robustness (computer science),Artificial intelligence,Synthetic biological circuit,Rational design,Machine learning,Directed evolution,Synthetic biology,Scalability
Journal
Volume
Issue
ISSN
21
2
1064-5462
Citations 
PageRank 
References 
2
0.58
3
Authors
3
Name
Order
Citations
PageRank
David Beneš120.92
P. Sosik2333.82
Alfonso Rodríguez-Patón343551.44