Name
Title | ||
|---|---|---|
A trimming-and-retrieving alignment scheme for reduced representation bisulfite sequencing. |
Abstract | ||
|---|---|---|
A Summary: Currently available bisulfite sequencing tools frequently suffer from low mapping rates and low methylation calls, especially for data generated from the Illumina sequencer, NextSeq. Here, we introduce a sequential trimming-and-retrieving alignment approach for investigating DNA methylation patterns, which significantly improves the number of mapped reads and covered CpG sites. The method is implemented in an automated analysis toolkit for processing bisulfite sequencing reads. |
Year | DOI | Venue |
|---|---|---|
2015 | 10.1093/bioinformatics/btv089 | BIOINFORMATICS |
Field | DocType | Volume |
Data mining,2 base encoding,Reduced representation bisulfite sequencing,Computer science,Bisulfite sequencing,DNA methylation,DNA sequencing,Bioinformatics,Trimming | Journal | 31 |
Issue | ISSN | Citations |
12 | 1367-4803 | 0 |
PageRank | References | Authors |
0.34 | 5 | 9 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Xuefeng Wang | 1 | 3 | 1.18 |
| Xiaoqing Yu | 2 | 2 | 0.80 |
| Wei Zhu | 3 | 63 | 10.82 |
| W Richard McCombie | 4 | 0 | 0.34 |
| Eric Antoniou | 5 | 0 | 0.34 |
| R Scott Powers | 6 | 0 | 0.34 |
| Nicholas O Davidson | 7 | 0 | 0.34 |
| Ellen Li | 8 | 0 | 0.34 |
| Jennie Williams | 9 | 0 | 0.34 |