Title
Classifying and Segmenting Microscopy Images Using Convolutional Multiple Instance Learning.
Abstract
Convolutional neural networks (CNN) have achieved state of the art performance on both classification and segmentation tasks. Applying CNNs to microscopy images is challenging due to the lack of datasets labeled at the single cell level. We extend the application of CNNs to microscopy image classification and segmentation using multiple instance learning (MIL). We present the adaptive Noisy-AND MIL pooling function, a new MIL operator that is robust to outliers. Combining CNNs with MIL enables training CNNs using full resolution microscopy images with global labels. We base our approach on the similarity between the aggregation function used in MIL and pooling layers used in CNNs. We show that training MIL CNNs end-to-end outperforms several previous methods on both mammalian and yeast microscopy images without requiring any segmentation steps.
Year
Venue
DocType
2015
CoRR
Journal
Volume
Citations 
PageRank 
abs/1511.05286
27
0.97
References 
Authors
14
3
Name
Order
Citations
PageRank
Oren Z. Kraus1270.97
Lei Jimmy Ba28887296.55
Brendan J. Frey33637404.51