Title
Interval scheduling maximizing minimum coverage
Abstract
In the classical interval scheduling type of problems, a set of n jobs, characterized by their start and end time, needs to be executed by a set of machines, under various constraints. In this paper we study a new variant in which the jobs need to be assigned to at most k identical machines, such that the minimum number of machines that are busy at the same time is maximized. This is relevant in the context of genome sequencing and haplotyping, specifically when a set of DNA reads aligned to a genome needs to be pruned so that no more than k reads overlap, while maintaining as much read coverage as possible across the entire genome. We show that the problem can be solved in time minO(n2logklogn),O(nklogk) by using max-flows. We also give an O(nlogn)-time approximation algorithm with approximation ratio =kk2.
Year
DOI
Venue
2015
10.1016/j.dam.2016.08.021
Discrete Applied Mathematics
Keywords
Field
DocType
Interval scheduling,Read pruning,Haplotype assembly,Max-flows
Discrete mathematics,Binary logarithm,Approximation algorithm,Combinatorics,Interval scheduling,Mathematics
Journal
Volume
Issue
ISSN
abs/1508.07820
C
0166-218X
Citations 
PageRank 
References 
3
0.39
5
Authors
4
Name
Order
Citations
PageRank
Veli Makinen151.45
valeria staneva230.39
Alexandru I. Tomescu310322.57
Daniel Valenzuela4356.65