Title
Bacwgstdb, A Database For Genotyping And Source Tracking Bacterial Pathogens
Abstract
Whole genome sequencing has become one of the routine methods in molecular epidemiological practice. In this study, we present BacWGSTdb (http://bacdb.org/BacWGSTdb), a bacterial whole genome sequence typing database which is designed for clinicians, clinical microbiologists and hospital epidemiologists. This database borrows the population structure from the current multi-locus sequence typing (MLST) scheme and adopts a hierarchical data structure: species, clonal complex and isolates. When users upload the pre-assembled genome sequences to BacWGSTdb, it offers the functionality of bacterial genotyping at both traditional MLST and whole-genome levels. More importantly, users are told which isolates in the public database are phylogenetically close to the query isolate, along with their clinical information such as host, isolation source, disease, collection time and geographical location. In this way, BacWGSTdb offers a rapid and convenient platform for worldwide users to address a variety of clinical microbiological issues such as source tracking bacterial pathogens.
Year
DOI
Venue
2016
10.1093/nar/gkv1004
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Genome,Genotyping,Genome project,Biology,Genomics,Multilocus sequence typing,Whole genome sequencing,Genetics,Database,Reference genome,Genotyping Techniques
Journal
44
Issue
ISSN
Citations 
D1
0305-1048
2
PageRank 
References 
Authors
0.41
7
2
Name
Order
Citations
PageRank
Zhi Ruan121.09
Ye Feng221.43