Paper Info
Title
Lynx: a knowledge base and an analytical workbench for integrative medicine.
Abstract
Lynx (http://lynx.ci.uchicago.edu) is a web-based database and a knowledge extraction engine. It supports annotation and analysis of high-throughput experimental data and generation of weighted hypotheses regarding genes and molecular mechanisms contributing to human phenotypes or conditions of interest. Since the last release, the Lynx knowledge base (LynxKB) has been periodically updated with the latest versions of the existing databases and supplemented with additional information from public databases. These additions have enriched the data annotations provided by Lynx and improved the performance of Lynx analytical tools. Moreover, the Lynx analytical workbench has been supplemented with new tools for reconstruction of co-expression networks and feature-and-network-based prioritization of genetic factors and molecular mechanisms. These developments facilitate the extraction of meaningful knowledge from experimental data and LynxKB. The Service Oriented Architecture provides public access to LynxKB and its analytical tools via user-friendly web services and interfaces.
Year
DOI
Venue
2016
10.1093/nar/gkv1257
NUCLEIC ACIDS RESEARCH
Field
DocType
Volume
Workbench,Annotation,Biology,Information retrieval,Knowledge extraction,Knowledge base,Bioinformatics,Molecular Sequence Annotation,Web service,Genetics,Service-oriented architecture,The Internet
Journal
44
Issue
ISSN
Citations 
D1
0305-1048
0
PageRank 
References 
Authors
0.34
34
13
Name
Order
Citations
PageRank
Dinanath Sulakhe118318.55
Bingqing Xie2233.23
Andrew Taylor310.68
Mark D'Souza4232.22
Sandhya Balasubramanian5101.91
Somaye Hashemifar6734.13
Steven White700.34
Utpal J. Dave8362.48
Gady Agam939143.99
Xu, Jinbo1088866.00
Sheng Wang1126528.52
T Conrad Gilliam12252.62
N Maltsev1323958.35