Name
Abstract | ||
|---|---|---|
Diseases due to infections might lead to death. Fever is often the first sign of an infection; other signs are skin hot to touch, shivering, aching muscles, pain, redness, swelling and so on, depending on the kind of infection. This study is a first attempt to model one of the infection symptoms, the edema. Briefly, edema may be caused by increased blood vessel wall permeability which lead to a swollen, red area. Neutrophil-bacteria iterations trigger a chain of cytokine reactions which in turn change the vessel wall permeability leading to an increase of interstitial fluid pressure. All the iterations are modeled using a n-phase partial differential equation system based on porous media assumptions. Model solutions are obtained using finite-volume method and the upwind scheme. Finally, the numerical results are qualitatively compared with experimental data available from the literature, presenting a good agreement. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1007/978-3-319-31744-1_30 | BIOINFORMATICS AND BIOMEDICAL ENGINEERING (IWBBIO 2016) |
Keywords | Field | DocType |
Computational immunology,Edema modeling,Porous media,Partial differential equations | Swelling,Edema,Interstitial fluid,Artificial intelligence,Shivering,Blood vessel,Computer vision,Immunology,Internal medicine,Cardiology,Permeability (electromagnetism),Upwind scheme,Engineering,Interstitial tissue | Conference |
Volume | ISSN | Citations |
9656 | 0302-9743 | 0 |
PageRank | References | Authors |
0.34 | 2 | 3 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Ruy Freitas Reis | 1 | 4 | 1.83 |
| weber dos santos r | 2 | 199 | 44.90 |
| Marcelo Lobosco | 3 | 95 | 24.89 |