Name
Abstract | ||
|---|---|---|
The CancerGrid approach to clinical trials information systems is based on a metamodel developed from the CONSORT statement of best practice in reporting randomised controlled trials. The metamodel is instantiated with metadata elements drawn from a repository, to create a model of a particular clinical trial. The model is then used to derive automatically a trial management system customized for that trial: generating electronic case report forms, configuring randomisation and eligibility services, and parameterising the security subsystem. The key benefits of the approach are a uniform mechanism for trial registration and discovery, reduced cost and rapid implementation of information systems, and shared semantics leading to improved opportunities for meta-analysis. We describe our implementation of this approach, and outline two applications: for a breast cancer study in the UK, and for a rheumatoid arthritis study run by the US Veterans' Health Administration. |
Year | DOI | Venue |
|---|---|---|
2009 | 10.1109/SEHC.2009.5069600 | SEHC@ICSE |
Field | DocType | Citations |
Information system,Management information systems,Metadata,Software engineering,Unified Modeling Language,Computer science,Consolidated Standards of Reporting Trials,Clinical trial,Management system,Metamodeling | Conference | 7 |
PageRank | References | Authors |
0.68 | 5 | 6 |
Name | Order | Citations | PageRank |
|---|---|---|---|
| Charles Crichton | 1 | 101 | 9.36 |
| Jim Davies | 2 | 673 | 80.95 |
| Jeremy Gibbons | 3 | 469 | 42.73 |
| Steve Harris | 4 | 55 | 7.37 |
| Andrew Tsui | 5 | 20 | 3.03 |
| James Brenton | 6 | 47 | 4.14 |