Title
Projecting the impact of implementing pre-exposure prophylaxis for HIV among men who have sex with men in Baltimore city.
Abstract
Men who have sex with men (MSM) experience over half of new HIV infections annually in Baltimore city. Oral pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) are likely to play central roles in reducing the risk of HIV transmission. However, the likely combined impact of these interventions remains uncertain. We propose an individual-based simulation approach to project the population-level impact of implementing PrEP for high-risk MSM in Baltimore, with different levels of coverage and adherence. The primary outcome is the HIV incidence over five years. We project non-linear relationships between program coverage, individual-level adherence, and population-level impact. The impact of PrEP increases with time but is not sustained if PrEP provision ceases. Expansion of ART coverage can augment the impact of PrEP on HIV incidence over the next decade.
Year
DOI
Venue
2015
10.1109/WSC.2015.7408439
Winter Simulation Conference
Field
DocType
ISSN
Gerontology,Psychological intervention,Systems engineering,Sociology,Men who have sex with men,Pre-exposure prophylaxis
Conference
0891-7736
ISBN
Citations 
PageRank 
978-1-5090-4484-9
0
0.34
References 
Authors
0
8