Title
Optimised Robust Treatment Plans for Prostate Cancer Focal Brachytherapy
Abstract
Focal brachytherapy is a clinical procedure that can be used to treat low-risk prostate cancer with reduced side-effects compared to conventional brachytherapy. Current practice is to man- ually plan the placement of radioactive seeds inside the prostate to achieve a desired treatment dose. Problems with the current practice are that the manual planning is time-consuming and high doses to the urethra and rectum cause undesirable side-effects. To address this problem, we have designed an optimisation algorithm that constructs treatment plans which achieve the desired dose while minimizing dose to organs at risk. We also show that these seed plans are robust to post-operative movement of the seeds within the prostate.
Year
DOI
Venue
2015
10.1016/j.procs.2015.05.225
Procedia Computer Science
Keywords
Field
DocType
optimization,brachytherapy,simulation
Computer science,Brachytherapy,Artificial intelligence,Prostate cancer,Medical physics,Prostate,Rectum,Machine learning
Conference
Volume
ISSN
Citations 
51
1877-0509
1
PageRank 
References 
Authors
0.35
1
7
Name
Order
Citations
PageRank
John M. Betts142.43
Christopher Mears2636.20
hayley m reynolds351.92
Guido Tack437727.56
Kevin Leo510.35
Martin A. Ebert610.35
annette haworth731.15