Title
Left and Right Atrial Contribution to the P-wave in Realistic Computational Models
Abstract
ECG markers derived from the P-wave are used frequently to assess atrial function and anatomy, e.g. left atrial enlargement. While having the advantage of being routinely acquired, the processes underlying the genesis of the P-wave are not understood in their entirety. Particularly the distinct contributions of the two atria have not been analyzed mechanistically. We used an in silico approach to simulate P-waves originating from the left atrium (LA) and the right atrium (RA) separately in two realistic models. LA contribution to the P-wave integral was limited to 30% or less. Around 20% could be attributed to the first third of the P-wave which reflected almost only RA depolarization. Both atria contributed to the second and last third with RA contribution being about twice as large as LA contribution. Our results foster the comprehension of the difficulties related to ECG-based LA assessment.
Year
DOI
Venue
2015
10.1007/978-3-319-20309-6_50
Lecture Notes in Computer Science
Keywords
DocType
Volume
Atrial modeling,Electrocardiogram,P-wave,Mathematical modeling,Left atrial enlargement
Conference
9126
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
5
6
Name
Order
Citations
PageRank
Axel Loewe11212.94
Martin W. Krueger29813.35
Pyotr G. Platonov393.73
Fredrik Holmqvist492.04
Olaf Dössel526456.10
Gunnar Seemann621248.50