Title
Computational Modelling of Low Voltage Resonant Drift of Scroll Waves in the Realistic Human Atria
Abstract
This study evaluated the effects of human atrial anatomy and fibre orientation on the effectiveness of a low voltage resonant defibrillation method. The Courtemanche-Ramirez-Nattel model was modified to simulate scroll wave re-entry that may represent a form of atrial fibrillation. The cell models were incorporated into a 3D anatomical model to simulate re-entry. The single shock threshold to eliminate re-entry in the isotropic and anisotropic 3D models was estimated as the reference point for the low energy defibrillation effectiveness. The low voltage scroll wave termination protocol was based on the resonant drift of stationary scroll waves due to feedback-controlled periodic stimulation. The global resonant feedback stimulation can work in the realistic anatomy model in principle. Further investigation to find optimal parameters for the resonant low energy defibrillation in anatomically realistic models must include optimal location of electrodes as well as stimulation protocol improvement.
Year
DOI
Venue
2015
10.1007/978-3-319-20309-6_48
Lecture Notes in Computer Science
Keywords
Field
DocType
Atrial arrhythmia,Electrical cardioversion,Computational cardiology,Mathematical modelling
Scroll,Isotropy,Atrium (architecture),Anisotropy,Defibrillation,Low energy,Simulation,Mechanics,Low voltage,Periodic graph (geometry),Physics
Conference
Volume
ISSN
Citations 
9126
0302-9743
1
PageRank 
References 
Authors
0.37
1
6
Name
Order
Citations
PageRank
Sanjay R Kharche111.38
Irina V. Biktasheva2115.39
Gunnar Seemann321248.50
Henggui Zhang410551.88
Jichao Zhao57015.63
Vadim N. Biktashev6235.74