Title
Dempster-Shafer Theory Based Feature Selection with Sparse Constraint for Outcome Prediction in Cancer Therapy.
Abstract
As a pivotal task in cancer therapy, outcome prediction is the foundation for tailoring and adapting a treatment planning. In this paper, we propose to use image features extracted from PET and clinical characteristics. Considering that both information sources are imprecise or noisy, a novel prediction model based on Dempster-Shafer theory is developed. Firstly, a specific loss function with sparse regularization is designed for learning an adaptive dissimilarity metric between feature vectors of labeled patients. Through minimizing this loss function, a linear low-dimensional transformation of the input features is then achieved; meanwhile, thanks to the sparse penalty, the influence of imprecise input features can also be reduced via feature selection. Finally, the learnt dissimilarity metric is used with the Evidential K-Nearest-Neighbor (EKNN) classifier to predict the outcome. We evaluated the proposed method on two clinical data sets concerning to lung and esophageal tumors, showing good performance.
Year
DOI
Venue
2015
10.1007/978-3-319-24574-4_83
Lecture Notes in Computer Science
Keywords
Field
DocType
Outcome Prediction,PET,Feature Selection,Sparse Constraint,Dempster-Shafer Theory
Feature vector,Data set,Feature selection,Pattern recognition,Feature (computer vision),Computer science,Cancer therapy,Regularization (mathematics),Artificial intelligence,Classifier (linguistics),Dempster–Shafer theory,Machine learning
Conference
Volume
ISSN
Citations 
9351
0302-9743
3
PageRank 
References 
Authors
0.40
0
5
Name
Order
Citations
PageRank
Chunfeng Lian113222.61
Ruan Su255953.00
Thierry Denoeux381574.98
Hua Li4459.03
Pierre Vera55910.15