Paper Info
Title
A Registration Approach to Endoscopic Laser Speckle Contrast Imaging for Intrauterine Visualisation of Placental Vessels.
Abstract
Intrauterine interventions such as twin-to-twin transfusion syndrome procedure require accurate mapping of the fetal placental vasculature to ensure complete photocoagulation of vascular anastomoses. However, surgeons are currently limited to fetoscopy and external ultrasound imaging, which are unable to accurately identify all vessels especially those that are narrow and at the periphery. Laser speckle contrast imaging LSCI is an optical method for imaging blood flow that is emerging as an intraoperative tool for neurosurgery. Here we explore the application of LSCI to minimally invasive fetal surgery, with an endoscopic LSCI system based on a 2.7-mm-diameter fetoscope. We establish using an optical phantom that it can image flow in 1-mm-diameter vessels as far as 4 mm below the surface. We demonstrate that a spatiotemporal algorithm produces the clearest images of vessels within 200 ms, and that speckle contrast images can be accurately registered using groupwise registration to correct for significant motion of target or probe. When tested on a perfused term ex vivo human placenta, our endoscopic LSCI system revealed small capillaries not evident in the fetoscopic images.
Year
DOI
Venue
2015
10.1007/978-3-319-24553-9_56
MICCAI
Field
DocType
Volume
Biomedical engineering,Image flow,Speckle pattern,Anastomosis,Imaging phantom,Artificial intelligence,Surgery,Fetal surgery,Medicine,Computer vision,Blood flow,Visualization,Fetoscopy
Conference
9349
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
3
9
Name
Order
Citations
PageRank
Gustavo Sato Dos Santos1274.10
Efthymios Maneas293.75
Daniil I. Nikitichev321.36
Anamaria Barburas400.34
Anna L. David5525.70
Jan Deprest612320.45
Adrien E. Desjardins7165.99
Tom Vercauteren81956108.68
Sébastien Ourselin92499237.61