Title | ||
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MUST-CNN: A Multilayer Shift-and-Stitch Deep Convolutional Architecture for Sequence-Based Protein Structure Prediction. |
Abstract | ||
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Predicting protein properties such as solvent accessibility and secondary structure from its primary amino acid sequence is an important task in bioinformatics. Recently, a few deep learning models have surpassed the traditional window based multilayer perceptron. Taking inspiration from the image classification domain we propose a deep convolutional neural network architecture, MUST-CNN, to predict protein properties. This architecture uses a novel multilayer shift-and-stitch (MUST) technique to generate fully dense per-position predictions on protein sequences. Our model is significantly simpler than the state-of-the-art, yet achieves better results. By combining MUST and the efficient convolution operation, we can consider far more parameters while retaining very fast prediction speeds. We beat the state-of-the-art performance on two large protein property prediction datasets. |
Year | Venue | DocType |
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2016 | THIRTIETH AAAI CONFERENCE ON ARTIFICIAL INTELLIGENCE | Journal |
Volume | Citations | PageRank |
abs/1605.03004 | 6 | 0.51 |
References | Authors | |
14 | 3 |
Name | Order | Citations | PageRank |
---|---|---|---|
Zeming Lin | 1 | 63 | 6.04 |
Jack Lanchantin | 2 | 65 | 8.01 |
Qi, Yanjun | 3 | 684 | 45.77 |