Title
Deriving ADHD biomarkers with sparse coding based network analysis
Abstract
Sparse coding has been increasingly used to explore brain networks using functional magnetic resonance imaging (fMRI). However, modeling and comparing brain network based on sparse coding is still challenging, especially in clinical applications. In this study, we propose a novel temporal sparse coding method to identify functional connectivity biomarkers in patients with Attention-Deficit/Hyperactivity Disorder (ADHD). Specifically, a group-wise temporal sparse coding method was proposed to localize corresponding brain regions of interest (ROIs) in rsfMRI data. The localized common ROIs were then used as brain network nodes for further functional connectivity analysis. By using a publicly available ADHD-200 dataset, we demonstrated that our method can identify functional connectivity biomarkers with improved performance in patient-healthy controls classification compared with the widely used independent component analysis (ICA).
Year
DOI
Venue
2015
10.1109/ISBI.2015.7163807
2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)
Keywords
Field
DocType
ADHD,temporal sparse coding,resting-state fMRI,functional connectivity,biomarkers
Functional magnetic resonance imaging,Pattern recognition,Neurophysiology,Neural coding,Computer science,Support vector machine,Resting state fMRI,Artificial intelligence,Independent component analysis,Network analysis,Machine learning,Encoding (memory)
Conference
ISSN
Citations 
PageRank 
1945-7928
0
0.34
References 
Authors
5
7
Name
Order
Citations
PageRank
Fangfei Ge144.93
Jinglei Lv220526.70
Xintao Hu311813.53
Bao Ge4296.07
Lei Guo51661142.63
Junwei Han63501194.57
Tianming Liu71033112.95