Title
Interactive exemplar-based segmentation toolkit for biomedical image analysis
Abstract
In the field of biomedical imaging analysis on single-cell level, reliable and fast segmentation of the cell nuclei from the background on three-dimensional images is highly needed for the further analysis. In this work we propose an interactive cell segmentation toolkit that first establishes a set of exemplar regions from user input through an easy and intuitive interface in both 2D and 3D in real-time, then extracts the shape and intensity features from those exemplars. Based on a local contrast-constrained region growing scheme, each connected component in the whole image would be filtered by the features from exemplars, forming an “exemplar-matching” group which passed the filtering and would be part of the final segmentation result, and a “non-exemplar-matching” group in which components would be further segmented by the gradient vector field based algorithm. The results of the filtering process are visualized back to the user in near real-time, thus enhancing the experience in exemplar selecting and parameter tuning. The toolkit is distributed as a plugin within the open source Vaa3D system (http://vaa3d.org).
Year
DOI
Venue
2015
10.1109/ISBI.2015.7163842
2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)
Keywords
Field
DocType
interactive image segmentation,learning based approach
Computer vision,Scale-space segmentation,Pattern recognition,Computer science,Image texture,Segmentation,Filter (signal processing),Segmentation-based object categorization,Image segmentation,Feature extraction,Artificial intelligence,Region growing
Conference
ISSN
Citations 
PageRank 
1945-7928
0
0.34
References 
Authors
8
6
Name
Order
Citations
PageRank
Xiang Li112615.50
Zhi Zhou215210.11
Philipp J. Keller3181.92
Hongkui Zeng4141.97
Tianming Liu51033112.95
Hanchuan Peng63930182.27