Title
Mining maximal subnetworks from interaction network with node attributes
Abstract
Detecting densely connected subgraphs is of great importance in sociology, biology and computer science disciplines where systems are often represented as a large graph. Several approaches have been proposed for detecting dense connected subgraphs in large graphs. Often these large graphs have additional attribute data characterizing either the nodes or edges of a graph. Recent research has combined the problem of dense connected subgraph detection with subspace similarity over attribute data. While detecting dense and cohesive subgraphs is desirable, the density factor can prevent the existing algorithms from reporting highly cohesive subgraphs which are not particularly dense. In this paper, we introduce an algorithm for mining maximal cohesive subgraphs from node attributed graphs. Unlike other approaches for detecting dense subgraphs, this algorithm does not require any density threshold. It discovers all maximal cohesive subgraphs regardless of their density. Experiments on real world datasets show that the proposed approach is effective in mining meaningful biological subgraphs from protein-protein interaction network, where attributes are extracted from gene expression datasets. We compare the proposed approach with the baseline technique, and results show that the proposed algorithm is much faster than the baseline algorithm.
Year
DOI
Venue
2015
10.1109/BIBM.2015.7359920
IEEE International Conference on Bioinformatics and Biomedicine
Field
DocType
ISSN
Graph,Data mining,Subspace topology,Computer science,Theoretical computer science,Interaction network,Vertex connectivity,Bioinformatics,Artificial neural network
Conference
2156-1125
Citations 
PageRank 
References 
0
0.34
6
Authors
3
Name
Order
Citations
PageRank
Aditya Goparaju121.11
Bassam Qormosh200.34
Saeed Salem318217.39