Title
Anisotropic Sampling Shape of White Matter Microstructure Cannot Cheat Diffusional Kurtosis.
Abstract
Diffusion kurtosis imaging is a newly developed diffusion magnetic resonance imaging technique, which is becoming increasingly valuable in clinical practice. Although low-resolution sampling is commonly used to compensate the unsteadiness of kurtosis estimation, the influence of the sampling shape has not been investigated. In this study, by using two different acquisition protocols, isotropic and anisotropic sampling voxels were acquired and their influence on various white matter structures was observed. Fiber tracking, T-tests, and correlation analysis were used to quantify the difference between the anisotropic and isotropic sampling. A significant difference (p < 0.01) was found in the fractional anisotropic level but not in kurtosis. The results presented here can provide a basis for higher resolution as well as higher quality kurtosis mapping, which may be of great significance in clinical examinations.
Year
Venue
Keywords
2016
JOURNAL OF ADVANCED COMPUTATIONAL INTELLIGENCE AND INTELLIGENT INFORMATICS
diffusion tensor imaging,diffusion kurtosis imaging,white matter,anisotropic sampling
Field
DocType
Volume
Statistical physics,Microstructure,Diffusion MRI,Anisotropy,White matter,Pattern recognition,Diffusion Kurtosis Imaging,Computer science,Sampling (statistics),Artificial intelligence,Kurtosis
Journal
20
Issue
ISSN
Citations 
4
1343-0130
0
PageRank 
References 
Authors
0.34
6
8
Name
Order
Citations
PageRank
Yuanyuan Chen111.38
Xin Zhao264.16
Miao Sha300.34
Yanan Liu400.34
jianguo ma500.68
hongyan ni600.68
Hongzhi Qi74920.61
Dong Ming810551.47