Paper Info
Title
A novel low-noise fully differential CMOS instrumentation amplifier with 1.88 noise efficiency factor for biomedical and sensor applications.
Abstract
In this paper, we present a novel instrumentation amplifier (INA) topology for mobile bio-medical data acquisition platforms. The proposed INA features a PMOS-NMOS complimentary transistor input pair biased in sub-threshold region to effectively boost the transconductance of the input pair and reduce the input referred noise. There are two embedded common-mode feedback circuits which help to establish the common-mode voltages without consuming extra power. One is at the output of the first stage (i.e. at the drain connection of the complimentary transistors) and the other at the final output stage. The INA provides a measured gain of 40dB and a bandwidth of 11kHz. The measured integrated noise is 0.78 µ V rms (50mHz to 11kHz) with measured CMRR of greater than 100dB. The proposed amplifier is versatile and hence capable of conditioning various bio-potential signals like Electrocardiogram (ECG), Electroencephalogram (EEG), Electromyogram (EMG) and Electrooculogram (EOG) as well as signals produced from sensors. A prototype chip has been fabricated in UMC 180nm mixed-mode CMOS technology operating at 1.8V power supply and occupying an area of 415 × 230 µ m 2 . The simulation and experimentally measured results are presented in this paper. NEF (noise efficiency factor) of 1.88 is obtained from measurement results. Hence the amplifier features for the first time a very low NEF (1.88) and high CMRR ( 100 dB ). A compact ExG conditioning and acquisition system has been developed and used to measure ECG, EEG, EMG and EOG signals from human subjects by deploying the proposed INA.
Year
DOI
Venue
2016
10.1016/j.mejo.2016.04.008
Microelectronics Journal
Keywords
Field
DocType
Instrumentation amplifier,Low-noise,Bio-potential,Electrocardiography,Noise efficiency factor,Common mode rejection ratio,Common mode feedback
Low-noise amplifier,Direct-coupled amplifier,Instrumentation amplifier,Electronic engineering,CMOS,Common-mode rejection ratio,Transconductance,Engineering,Effective input noise temperature,Electrical engineering,Amplifier
Journal
Volume
Issue
ISSN
53
C
0026-2692
Citations 
PageRank 
References 
3
0.50
6
Authors
5
Name
Order
Citations
PageRank
Devarshi Mrinal Das1103.89
Abhishek Srivastava28822.03
J. Ananthapadmanabhan350.96
Meraj Ahmad481.72
Maryam Shojaei Baghini58629.67