Name
Title | ||
|---|---|---|
Hypothetical biomolecular probe based on a genetic switch with tunable symmetry and stability. |
Abstract | ||
|---|---|---|
BackgroundGenetic switches are ubiquitous in nature, frequently associated with the control of cellular functions and developmental programs. In the realm of synthetic biology, it is of great interest to engineer genetic circuits that can change their mode of operation from monostable to bistable, or even to multistable, based on the experimental fine-tuning of readily accessible parameters. In order to successfully design robust, bistable synthetic circuits to be used as biomolecular probes, or understand modes of operation of such naturally occurring circuits, we must identify parameters that are key in determining their characteristics. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1186/s12918-016-0279-y | BMC Systems Biology |
Keywords | Field | DocType |
Genetic toggle switch, Stochastic gene expression, LacI-TetR system, Nano-recorder | Bistability,Biology,Systems biology,Stochastic process,Multivibrator,Bioinformatics,Gene regulatory network,Electronic circuit,Synthetic biology | Journal |
Volume | Issue | ISSN |
10 | 1 | 1752-0509 |
Citations | PageRank | References |
0 | 0.34 | 2 |
Authors | ||
4 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| Nikolay Martyushenko | 1 | 0 | 0.34 |
| Sigurd Hagen Johansen | 2 | 0 | 0.34 |
| Cheol-Min Ghim | 3 | 6 | 0.85 |
| Eivind Almaas | 4 | 50 | 8.30 |