Paper Info
Title
MEG Analysis of Neural Interactions in Attention-Deficit/Hyperactivity Disorder
Abstract
AbstractThe aim of the present study was to explore the interchannel relationships of resting-state brain activity in patients with attention-deficit/hyperactivity disorder ADHD, one of the most common mental disorders that develop in children. Magnetoencephalographic MEG signals were recorded using a 148-channel whole-head magnetometer in 13 patients with ADHD range: 8–12 years and 14 control subjects range: 8–13 years. Three complementary measures coherence, phase-locking value, and Euclidean distance were calculated in the conventional MEG frequency bands: delta, theta, alpha, beta, and gamma. Our results showed that the interactions among MEG channels are higher for ADHD patients than for control subjects in all frequency bands. Statistically significant differences were observed for short-distance values within right-anterior and central regions, especially at delta, beta, and gamma-frequency bands p<0.05; Mann-Whitney U test with false discovery rate correction. These frequency bands also showed statistically significant differences in long-distance interactions, mainly among anterior and central regions, as well as among anterior, central, and other areas. These differences might reflect alterations during brain development in children with ADHD. Our results support the role of frontal abnormalities in ADHD pathophysiology, which may reflect a delay in cortical maturation in the frontal cortex.
Year
DOI
Venue
2016
10.1155/2016/8450241
Periodicals
Field
DocType
Volume
Attention deficit hyperactivity disorder,Mann–Whitney U test,Alpha (ethology),Brain activity and meditation,Artificial intelligence,Audiology,Beta (finance),Brain development,Developmental psychology,False discovery rate,Pattern recognition,Psychology,Magnetoencephalography
Journal
2016
Issue
ISSN
Citations 
1
1687-5265
0
PageRank 
References 
Authors
0.34
2
7
Name
Order
Citations
PageRank
Amine Khadmaoui100.34
Carlos Gómez28615.72
Jesús Poza35512.29
Alejandro Bachiller462.95
Alberto Fernández55311.82
Javier Quintero600.34
Roberto Hornero760367.74