Name
Abstract | ||
|---|---|---|
Post mortem imaging is playing an increasingly important role in perinatal autopsy, and correct interpretation of imaging changes is paramount. This is particularly important following intra-uterine fetal death, where there may be fetal maceration. The aim of this study was to investigate whether any changes seen on a whole body fetal post mortem magnetic resonance imaging (PMMR) correspond to maceration at conventional autopsy.We performed pre-autopsy PMMR in 75 fetuses using a 1.5 Tesla Siemens Avanto MR scanner (Erlangen, Germany). PMMR images were reported blinded to the clinical history and autopsy data using a numerical severity scale (0 = no maceration changes to 2 = severe maceration changes) for 6 different visceral organs (total 12). The degree of maceration at autopsy was categorized according to severity on a numerical scale (1 = no maceration to 4 = severe maceration). We also generated quantitative maps to measure the liver and lung T2.The mean PMMR maceration score correlated well with the autopsy maceration score (R (2) = 0.93). A PMMR score of ≥4.5 had a sensitivity of 91 %, specificity of 64 %, for detecting moderate or severe maceration at autopsy. Liver and lung T2 were increased in fetuses with maceration scores of 3-4 in comparison to those with 1-2 (liver p = 0.03, lung p = 0.02).There was a good correlation between PMMR maceration score and the extent of maceration seen at conventional autopsy. This score may be useful in interpretation of fetal PMMR. |
Year | DOI | Venue |
|---|---|---|
2016 | 10.1186/s12880-016-0137-9 | BMC Medical Imaging |
Keywords | Field | DocType |
Autopsy,Fetuses,Intrauterine death,MRI,Maceration,Pathology | Maceration (wine),Fetus,Autopsy,Intrauterine death,Post mortem magnetic resonance imaging,Radiology,Medicine,Pathology,Magnetic resonance imaging | Journal |
Volume | Issue | ISSN |
16 | 1 | 1471-2342 |
Citations | PageRank | References |
0 | 0.34 | 0 |
Authors | ||
8 | ||
Name | Order | Citations | PageRank |
|---|---|---|---|
| P. Montaldo | 1 | 0 | 0.34 |
| S. Addison | 2 | 0 | 0.34 |
| V. Oliveira | 3 | 0 | 0.34 |
| P. J. Lally | 4 | 0 | 0.34 |
| A. M. Taylor | 5 | 0 | 0.34 |
| N. J. Sebire | 6 | 0 | 1.01 |
| S. Thayyil | 7 | 4 | 0.77 |
| Owen J. Arthurs | 8 | 0 | 0.68 |