Title
Automated 5-year mortality prediction using deep learning and radiomics features from chest computed tomography
Abstract
In this paper, we propose new prognostic methods that predict 5-year mortality in elderly individuals using chest computed tomography (CT). The methods consist of a classifier that performs this prediction using a set of features extracted from the CT image and segmentation maps of multiple anatomic structures. We explore two approaches: 1) a unified framework based on two state-of-the-art deep learning models extended to 3-D inputs, where features and classifier are automatically learned in a single optimisation process; and 2) a multi-stage framework based on the design and selection and extraction of hand-crafted radiomics features, followed by the classifier learning process. Experimental results, based on a dataset of 48 annotated chest CTs, show that the deep learning models produces a mean 5-year mortality prediction AUC in [68.8%,69.8%] and accuracy in [64.5%,66.5%], while radiomics produces a mean AUC of 64.6% and accuracy of 64.6%. The successful development of the proposed models has the potential to make a profound impact in preventive and personalised healthcare.
Year
DOI
Venue
2017
10.1109/ISBI.2017.7950485
2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017)
Keywords
DocType
Volume
deep learning,radiomics,feature learning,hand-designed features,computed tomography,five-year mortality
Conference
abs/1607.00267
ISBN
Citations 
PageRank 
978-1-5090-1173-5
0
0.34
References 
Authors
0
5
Name
Order
Citations
PageRank
Gustavo Carneiro129227.63
Luke Oakden-Rayner240.75
Andrew P. Bradley32087195.95
Jacinto C. Nascimento439640.94
Lyle J. Palmer5733.10