Title
Predicting structured metadata from unstructured metadata.
Abstract
Enormous amounts of biomedical data have been and are being produced by investigators all over the world. However, one crucial and limiting factor in data reuse is accurate, structured and complete description of the data or data about the data-defined as metadata. We propose a framework to predict structured metadata terms from unstructured metadata for improving quality and quantity of metadata, using the Gene Expression Omnibus (GEO) microarray database. Our framework consists of classifiers trained using term frequency-inverse document frequency (TF-IDF) features and a second approach based on topics modeled using a Latent Dirichlet Allocation model (LDA) to reduce the dimensionality of the unstructured data. Our results on the GEO database show that structured metadata terms can be the most accurately predicted using the TF-IDF approach followed by LDA both outperforming the majority vote baseline. While some accuracy is lost by the dimensionality reduction of LDA, the difference is small for elements with few possible values, and there is a large improvement over the majority classifier baseline. Overall this is a promising approach for metadata prediction that is likely to be applicable to other datasets and has implications for researchers interested in biomedical metadata curation and metadata prediction.
Year
DOI
Venue
2016
10.1093/database/baw080
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION
DocType
Volume
ISSN
Journal
2016
1758-0463
Citations 
PageRank 
References 
1
0.36
8
Authors
4
Name
Order
Citations
PageRank
Lisa Posch1195.44
Maryam Panahiazar2356.53
Michel Dumontier389893.35
Olivier Gevaert415414.64