Title
Novel risk index for the identification of age-related macular degeneration using radon transform and DWT features.
Abstract
Age-related Macular Degeneration (AMD) affects the central vision of aged people. It can be diagnosed due to the presence of drusen, Geographic Atrophy (GA) and Choroidal Neovascularization (CNV) in the fundus images. It is labor intensive and time-consuming for the ophthalmologists to screen these images. An automated digital fundus photography based screening system can overcome these drawbacks. Such a safe, non-contact and cost-effective platform can be used as a screening system for dry AMD. In this paper, we are proposing a novel algorithm using Radon Transform (RT), Discrete Wavelet Transform (DWT) coupled with Locality Sensitive Discriminant Analysis (LSDA) for automated diagnosis of AMD. First the image is subjected to RT followed by DWT. The extracted features are subjected to dimension reduction using LSDA and ranked using t-test. The performance of various supervised classifiers namely Decision Tree (DT), Support Vector Machine (SVM), Probabilistic Neural Network (PNN) and k-Nearest Neighbor (k-NN) are compared to automatically discriminate to normal and AMD classes using ranked LSDA components. The proposed approach is evaluated using private and public datasets such as ARIA and STARE. The highest classification accuracy of 99.49%, 96.89% and 100% are reported for private, ARIA and STARE datasets. Also, AMD index is devised using two LSDA components to distinguish two classes accurately. Hence, this proposed system can be extended for mass AMD screening.
Year
DOI
Venue
2016
10.1016/j.compbiomed.2016.04.009
Comp. in Bio. and Med.
Keywords
Field
DocType
Age-related macular degeneration,Computed aided diagnosis,Discrete wavelet transform,Fundus imaging,Locality sensitive discriminant analysis,Radon transform
Decision tree,Computer vision,Dimensionality reduction,Pattern recognition,Computer science,Support vector machine,Fundus (eye),Probabilistic neural network,Artificial intelligence,Discrete wavelet transform,Radon transform,Fundus photography
Journal
Volume
Issue
ISSN
73
C
0010-4825
Citations 
PageRank 
References 
15
0.66
24
Authors
10
Name
Order
Citations
PageRank
Rajendra Acharya U14666296.34
Muthu Rama Krishnan Mookiah22359.94
Joel E. W. Koh326619.06
Jen-Hong Tan474532.04
Kevin Noronha51014.69
Sulatha V. Bhandary627113.76
A. Krishna Rao7914.46
Yuki Hagiwara864129.34
Chua Kuang Chua954526.57
Augustinus Laude1022111.99