Title
Integration of a Droplet-Based Microfluidic System and Silicon Nanoribbon FET Sensor.
Abstract
We present a novel microfluidic system that integrates droplet microfluidics with a silicon nanoribbon field-effect transistor (SiNR FET), and utilize this integrated system to sense differences in pH. The device allows for selective droplet transfer to a continuous water phase, actuated by dielectrophoresis, and subsequent detection of the pH level in the retrieved droplets by SiNR FETs on an electrical sensor chip. The integrated microfluidic system demonstrates a label-free detection method for droplet microfluidics, presenting an alternative to optical fluorescence detection. In this work, we were able to differentiate between droplet trains of one pH-unit difference. The pH-based detection method in our integrated system has the potential to be utilized in the detection of biochemical reactions that induce a pH-shift in the droplets.
Year
DOI
Venue
2016
10.3390/mi7080134
MICROMACHINES
Keywords
Field
DocType
NanoFET,silicon nanoribbon,droplet microfluidics,pH measurement
Nanotechnology,Microfluidics,Electronic engineering,Transistor,Drop (liquid),Materials science,Silicon
Journal
Volume
Issue
ISSN
7
8
2072-666X
Citations 
PageRank 
References 
0
0.34
2
Authors
6