Abstract | ||
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Cell tissue construction is one of the important issues for tissue engineering, which is a key-technology in regenerative medicine. Recently, several studies have reported, the in vitro fabrication of simple cell tissues. However, organs are made of some kinds of cells and they are complex tissues. Therefore, a technology to reproduce the complex structure and biological function of the organ is needed. In this paper, we propose an automated system for the construction of a cell tissue in vitro, based on hydrogel fiber. We fabricate the cell tissues with some kinds of gel fibers, and the tissues with fine arbitrary shape structures. To evaluate the proposed system, a fine lattice structure was constructed as an example of cell tissue form. Furthermore, we designed a gel fiber discharge nozzle using laminar flow, and fabricated the lattice structure using laminar flow fiber. Through the experiments of the lattice shape structure construction, we observed the cell growth in the constructed lattice form, which proves the functionality of the structure. Moreover, we fabricated 3-laminar flow fibers, and we will fabricate more functional cell tissues. |
Year | Venue | Field |
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2015 | MHS | Biomedical engineering,Fiber,Laminar flow,Simple cell,Regenerative medicine,Cell growth,Tissue engineering,Engineering,Fabrication,Nozzle |
DocType | Citations | PageRank |
Conference | 0 | 0.34 |
References | Authors | |
0 | 8 |
Name | Order | Citations | PageRank |
---|---|---|---|
Masaru Kojima | 1 | 35 | 25.71 |
Mitsuhiro Horade | 2 | 5 | 8.97 |
Akira Fukushima | 3 | 0 | 0.68 |
Kenichi Ohara | 4 | 150 | 42.58 |
Shinji Sakai | 5 | 0 | 0.34 |
Kazuto Kamiyama | 6 | 3 | 6.51 |
Yasushi Mae | 7 | 321 | 77.50 |
Tatsuo Arai | 8 | 728 | 177.57 |