Title
Mean Values of Gene Duplication and Loss Cost Functions.
Abstract
Reconciliation based cost functions play crucial role in comparing gene family trees with their species tree. To provide a better understanding of tree reconciliation we derive mean formulas for gene duplication, gene loss and gene duplication-loss cost functions, for a fixed species tree under the uniform model of gene trees. We then analyse the time complexity and study mathematical properties of these formulas. Finally, we provide several computational experiments on empirical datasets for the duplication, duplication-loss and deep coalescence means under the uniform model.
Year
DOI
Venue
2016
10.1007/978-3-319-38782-6_16
BIOINFORMATICS RESEARCH AND APPLICATIONS, ISBRA 2016
Keywords
Field
DocType
Tree reconciliation,Duplication-loss model,Deep coalescence,Speciation,Gene duplication,Gene loss,Bijectively labelled tree,Uniform model of trees,Mean value
Gene,Mean value,Computer science,Artificial intelligence,Computational biology,Time complexity,Gene duplication,Mathematical properties,Gene family,Machine learning
Conference
Volume
ISSN
Citations 
9683
0302-9743
1
PageRank 
References 
Authors
0.37
14
3
Name
Order
Citations
PageRank
Pawel Górecki111214.26
Jaroslaw Paszek273.23
Agnieszka Mykowiecka311922.47