Title
Accurate Quantification of Glandularity and Its Applications with Regard to Breast Radiation Doses and Missed Lesion Rates During Individualized Screening Mammography.
Abstract
Mammography, the most effective early breast cancer detection technique, is associated with the risk of missed lesions in dense breasts, and excessive X-ray exposure. Accurate estimations of glandularity and radiation dose are important during screening. We propose a novel, inexpensive method for accurate glandularity quantification using pixel values in clinical digital mammograms and X-ray exposure spectra. Glandularities were calculated for 314 mammograms in Japanese women, and the Dance formula c-factor was applied to estimate breast doses. To investigate the relationship between breast thickness and missed lesions, images were classified into four categories based on the rate of missed lesions, and correlated with breast thickness. Glandularity decreased with increasing compressed breast thickness, indicating that commonly used breast doses assumed 50% glandularity significantly overestimate thin breasts and underestimate thick breasts. The missed lesion rate was higher for thinner compressed breast thicknesses. Accurate glandularity estimation could thus promote individualized screening mammography.
Year
DOI
Venue
2016
10.1007/978-3-319-41546-8_47
Digital Mammography / IWDM
Keywords
DocType
Volume
Individualized screening mammography,Glandularity,Breast dose,X-ray spectrum,Missed lesion rate
Conference
9699
ISSN
Citations 
PageRank 
0302-9743
0
0.34
References 
Authors
0
7
Name
Order
Citations
PageRank
Mika Yamamuro100.68
Kanako Yamada200.34
Yoshiyuki Asai3307.56
Koji Yamada400.34
Yoshiaki Ozaki500.34
Masao Matsumoto600.34
Takamichi Murakami791.89