Title
Automatic Neuron Tracing Using a Locally Tunable Approach
Abstract
Neuroscience has been interested in cellular neuroanatomy since the time of Ramón y Cajal. Although the manual reconstruction of neuron morphologies is still widely used, the recent availability of large image data asks for automatic or semi-automatic tools. In this paper we present an automatic method to trace neurites in 3D volumes based on two main steps. The first detects neurites connected with a given seed that satisfy a conservative membership rule, the second detects weak neurite chunks allowing a local growth of the arbor on the basis of local intensity features. The local step also accommodates to the nonuniform illumination and to the noise of the sample. We tested our proposal on the Olfactory Projection dataset belonging to the well-known DIADEM challenge, comparing its performance against those achieved by other state-of-the-art methods available within the BigNeuron Project.
Year
DOI
Venue
2016
10.1109/CBMS.2016.48
2016 IEEE 29th International Symposium on Computer-Based Medical Systems (CBMS)
Keywords
Field
DocType
Neuron tracing,BigNeuron,Neuron image analysis,Neuron reconstruction
Iterative reconstruction,Computer vision,Computer science,Artificial intelligence,Neuroanatomy,Tracing
Conference
ISSN
ISBN
Citations 
2372-9198
978-1-4673-9037-8
1
PageRank 
References 
Authors
0.35
18
3
Name
Order
Citations
PageRank
Ludovica Acciai120.70
Paolo Soda240739.44
Giulio Iannello341446.75